cure him of the disease has shown "remarkable" progress,
doctors have told a newspaper.
Scientists treating the 44-year-old patient are now hopeful of
a breakthrough in what has been described as "one of the
first serious attempts at a full cure for HIV*.
*Results showed the man's most recent blood test showed no
detectable HIV was present.
Results showed the man's most recent blood test showed no
detectable HIV was present.
The man, who has remained anonymous, is the first of 50
people to complete a trial using the two-stage attack on the
deadly virus.*
*The research is being carried out by a collaboration of five of
Britain's top universities organised by the National Health
Service.
Mark Samuels, managing director of the National Institute for
Health Research Office for Clinical Research Infrastructure,
told the Sunday Times: "This is one of the first serious
attempts at a full cure for HIV. We are exploring the real
possibility of curing HIV.*
*"This is a huge challenge and it's still early days but the
progress has been remarkable."
The trial patient told the newspaper that recent blood tests
showed no detectable HIV virus was present, although it was
too early to confirm that the treatment had worked.*
*The new therapy aims to overcome a major barrier to clearing
the virus from a sufferer's body that has challenged
researchers for decades.
Current methods using antiretroviral therapies (Art) fall short
of ridding patients of HIV, as the virus can hide out of the
drugs' reach in the immune system's T-cells.*
*By sheltering in dormant T-cells the virus can later take over
its host and use it to produce thousands of copies of itself,
should Art no longer work.
The research by Oxford and Cambridge universities, Imperial
College London, University College London, and King's
College London, is testing a "kick and kill" technique to first
expose, then destroy the virus.*
*First a vaccine helps the body find infected T-cells. This is
then followed by a course of the drug Vorinostat that
awakens the dormant T-cells, which then begin producing
HIV proteins that act as a homing beacon to the immune
system.
Imperial College London consultant physician Professor
Sarah Fidler said the treatment worked in the laboratory and
there was "good evidence" it will work in patients.
However she added: "We must stress we are still a long way
from any actual therapy *
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